Author

D. Holmes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Lovley· 3 shared J. Zhou· 3 shared T. Ueki· 2 shared A. Brewster· 1 shared A. C. Pearce· 1 shared A. Denis· 1 shared A. Dossang· 1 shared A. M. Jagger· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

D. Lovley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Different Routes for Direct Interspecies Electron Transfer with Diverse Electron-Accepting Partners

D. Holmes, J. Zhou, J. A. Smith, C. Wang, X. Liu, D. Lovley

This study compares the transcriptomes of Geobacter metallireducens during DIET with different electron-accepting partners, showing varied gene expression and requirements for DIET.

bioRxiv · Apr 27, 2022 · PreprintMicrobiology

Mechanisms for Electron Uptake by Methanosarcina acetivorans During Direct Interspecies Electron Transfer

D. Holmes, J. Zhou, T. Ueki, T. Woodard, D. Lovley

This study identifies MmcA as a key outer-surface c-type cytochrome for DIET in M. acetivorans and shows that archaella and other membrane complexes are involved in electron processing for methane production.

bioRxiv · Jun 11, 2021Microbiology

Development of a small molecule that corrects misfolding and increases secretion of Z α1-antitrypsin

D. Lomas, J. A. Irving, C. Arico-Muendel, S. Belyanskaya, A. Brewster, M. J. B. Brown, C.-w. Chung, H. Dave, A. Denis, N. Dodic, A. Dossang, P. Eddershaw, D. Klimaszewska, I. Haq, D. Holmes, , A. C. Pearce

This study identifies a small molecule that stabilizes Z α1-antitrypsin, reduces polymerization, and increases its secretion in cells and mice.

bioRxiv · Jul 26, 2020Pharmacology & Toxicology

A Membrane-Bound Cytochrome Enables Methanosarcina acetivorans to Conserve Energy to Support Growth from Extracellular Electron Transfer

D. Holmes, T. Ueki, H.-Y. Tang, J. Zhou, J. Smith, G. Chaput, D. Lovley

This study shows Methanosarcina acetivorans conserves energy via extracellular electron transfer using a membrane-bound cytochrome, MmcA, and identifies its role in electron transport pathways.

bioRxiv · Mar 26, 2019 · PreprintMicrobiology