Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes
C. Fihn, H. Lembke, J. Gaulin, P. Bouchard, A. R. Villarreal, M. R. Penningroth, K. Crone, G. Vogt, A. Gilbertsen, Y. Ayotte, L. CouthinodeOliveira, M. Serrano-Wu, N. Drouin, D. Hung, R. C. Hunter, E. E. Carlson
The paper evaluates a library of 2-aminobenzothiazole compounds targeting the CA domain of histidine kinases, finding they reduce virulence in Pseudomonas aeruginosa.
bioRxiv · May 2, 2023 · PreprintMicrobiology