Author

D. J. Mole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

J. P. Iredale· 2 shared J. R. Portman· 2 shared N. C. Henderson· 2 shared R. Dobie· 2 shared B. E. Henderson· 1 shared B. E. P. Henderson· 1 shared C. Benezech· 1 shared C. J. Weston· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

J. P. Iredale

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics

P. Ramachandran, R. Dobie, J. R. Wilson-Kanamori, E. F. Dora, B. E. Henderson, R. S. Taylor, K. P. Matchett, J. R. Portman, M. Efremova, R. Vento-Tormo, N. T. Luu, C. J. Weston, P. N. Newsome, E. M. Harrison, D. J. Mole, , N. C. Henderson

This study uses single-cell transcriptomics to identify novel fibrotic cell types and interactions in human liver cirrhosis, revealing potential therapeutic targets.

Nature · Oct 9, 2019Peer-reviewedImmunology

Neutrophils mediate the capture of peritoneal contaminants by fat-associated lymphoid clusters of the omentum

L. H. Jackson-Jones, P. Smith, M. S. Magalhaes, J. R. Portman, K. J. Mylonas, M. Nixon, B. E. P. Henderson, R. Dobie, N. C. Henderson, D. J. Mole, C. Benezech

This study identifies FALC cover cells expressing CXCL1 that recruit neutrophils to neutralize peritoneal contaminants, confirmed in human appendicitis.

bioRxiv · Sep 18, 2019 · PreprintImmunology

Detecting Drug-Target Binding In Cells Using Fluorescence Activated Cell Sorting Coupled With Mass Spectrometry Analysis

K. Wilson, S. P. Webster, J. P. Iredale, X. Zheng, N. Z. M. Homer, N. Pham, M. Auer, D. J. Mole

This paper introduces a new method called TAPS to assess drug-target binding in cells, demonstrating its effectiveness with the challenging KMO target.

bioRxiv · Apr 3, 2017Pharmacology & Toxicology