Author

D. J. Wcisel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Dornburg· 3 shared J. A. Yoder· 3 shared A. W. Thompson· 1 shared C. Nguyen· 1 shared E. Ferraro· 1 shared G. W. Litman· 1 shared I. Braasch· 1 shared J. Andrade· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

A. Dornburg

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3 papers

Recent·Most cited

Ancient Fish Lineages Illuminate Toll-Like Receptor Diversification in Early Vertebrate Evolution

K. B. Carlson, C. Nguyen, D. J. Wcisel, J. A. Yoder, A. Dornburg

This study investigates the diversification of Toll-like receptors (TLRs) across vertebrate evolution using genomic and transcriptomic data, revealing new TLR clades and gene loss patterns linked to adaptive immune system development.

bioRxiv · Apr 5, 2023Evolutionary Biology

A highly diverse set of novel immunoglobulin-like transcript (NILT) genes in zebrafish indicates a wide range of functions with complex relationships to mammalian receptors

D. J. Wcisel, A. Dornburg, S. C. McConnell, K. M. Hernandez, J. Andrade, J. L. O. de Jong, G. W. Litman, J. A. Yoder

The paper identifies a highly diverse set of NILT genes in zebrafish, revealing complex relationships to mammalian receptors and suggesting multiple roles in host immunity.

bioRxiv · Apr 21, 2022Immunology

Holosteans contextualize the role of the teleost genome duplication in promoting the rise of evolutionary novelties in the ray-finned fish innate immune system

A. Dornburg, D. J. Wcisel, K. Zapfe, E. Ferraro, L. Roupe-Abrams, A. W. Thompson, I. Braasch, T. Ota, J. A. Yoder

This study investigates the innate immune receptor diversity in Holostei, showing that their gene families predate the teleost genome duplication and rival teleost diversity, challenging assumptions about the TGD's role in immune innovation.

bioRxiv · Jun 11, 2021Immunology