Author

T. Ota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

A. Dornburg· 1 shared A. Kawamoto· 1 shared A. Malbari· 1 shared A. Tanaka· 1 shared A. W. Thompson· 1 shared B. D. Engel· 1 shared B. Gallet· 1 shared C. Aranda· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Dornburg

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

Y. Tsugawa, K. Furukawa, T. Ise, M. Takayama, T. Ota, T. Kuroda, S. Shano, T. Hashimoto, H. Konishi, T. Ishihara, M. Sato, H. Kamada, K. Fukao, T. Shishido, T. Takahashi, S. Nagata

This study identifies an antibody, CV804, that targets the conserved S2 domain of coronaviruses and shows broad cross-reactivity and ADCC activity against SARS-CoV-2 and related viruses.

bioRxiv · Feb 28, 2024Microbiology

Modifiable clinical dental impression methods to obtain whole-mouth and detailed dental traits from vertebrates

J. N. Wibisana, R. Sallan, T. Ota, P. Puchenkov, T. Kubo, L. Sallan

This study introduces a non-destructive method using a printable tray to capture high-resolution dental traits in vertebrates, enabling in-vivo and museum specimen analysis.

bioRxiv · Nov 21, 2023Evolutionary Biology

Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation

G. Shimakawa, M. Demulder, S. Flori, A. Kawamoto, Y. Tsuji, H. Nawaly, A. Tanaka, R. Tohda, T. Ota, H. Matsui, N. Morishima, R. Okubo, W. Wietrzynski, L. Lamm, R. D. Righetto, , Y. Matsuda

This study identifies a protein shell surrounding diatom pyrenoids that enhances CO2 fixation efficiency and reveals its structural and functional role through in vivo and in vitro analyses.

bioRxiv · Oct 25, 2023 · PreprintCell Biology

The memory of pathogenic IgE is contained within CD23+IgG1+ memory B cells poised to switch to IgE in food allergy

M. Ota, K. Hoehn, T. Ota, C. Aranda, S. Friedman, W. Braga, A. Malbari, S. Kleinstein, S. Sicherer, M. Curotto de Lafaille

The paper identifies CD23+IgG1+ memory B cells in peanut allergy that can switch to IgE and contain high affinity allergen-specific clones.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Holosteans contextualize the role of the teleost genome duplication in promoting the rise of evolutionary novelties in the ray-finned fish innate immune system

A. Dornburg, D. J. Wcisel, K. Zapfe, E. Ferraro, L. Roupe-Abrams, A. W. Thompson, I. Braasch, T. Ota, J. A. Yoder

This study investigates the innate immune receptor diversity in Holostei, showing that their gene families predate the teleost genome duplication and rival teleost diversity, challenging assumptions about the TGD's role in immune innovation.

bioRxiv · Jun 11, 2021Immunology