Fibroblast growth factor-21 induces skeletal muscle atrophy and increases plasma amino acids in female mice: a potential role for glucocorticoids
K. R. Larson, D. Jayakrishnan, K. Soto Sauza, M. L. Goodson, A. T. Chaffin, A. Davidyan, S. Pathak, Y. Fang, D. Gonzalez Magana, B. F. Miller, K. K. Ryan
This study shows FGF21 induces skeletal muscle atrophy and increases plasma amino acids in female mice, likely via glucocorticoid signaling and HPA axis activation.
bioRxiv · Jun 27, 2023 · PreprintPhysiology