Author

D. Kostomiris

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Drelich· 1 shared A. E. Clark· 1 shared A. F. Carlin· 1 shared A. Katzfuss· 1 shared A. O'Donoghue· 1 shared B. C. Chenna· 1 shared B. L. Hurst· 1 shared C.-T. Tseng· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Drelich

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1 paper

Recent·Most cited

A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells

D. Mellott, C.-T. Tseng, A. Drelich, P. Fajtova, B. C. Chenna, D. Kostomiris, J. C. Hsu, J. Zhu, Z. Taylor, V. Tat, A. Katzfuss, L. Li, M. A. Giardini, D. Skinner, K. Hirata, , J. H. McKerrow

This paper shows that K777, a cysteine protease inhibitor, blocks SARS-CoV-2 infection by inhibiting host cathepsin L, which is required for spike protein processing, with nanomolar efficacy in several cell lines.

bioRxiv · Oct 23, 2020 · PreprintBiochemistry