The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties
L. Tattersall, K. M. Shah, D. L. Lath, A. Singh, J. M. Down, E. De Marchi, A. Williamson, F. Di Virgilio, D. Heymann, E. Adinolfi, W. D. Fraser, D. Green, M. A. Lawson, A. Gartland
This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.
bioRxiv · May 7, 2021Cancer Biology