MicrobiologybioRxivPreprint
A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity
DOI 10.1101/2022.01.27.477972
Author
M. A. Lawson
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2017-2022 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 11 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship7 papers
Recent·Most cited
- ImmunologybioRxiv
The polyanionic drug suramin neutralizes histones and prevents endotheliopathy
N. Villalba, A. M. Sackheim, M. A. Lawson…·K. Freeman
This paper shows suramin neutralizes histones, preventing endothelial damage and improving vascular function in inflammatory conditions.
DOI 10.4049/jimmunol.2200703 - Cancer BiologybioRxiv
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties
L. Tattersall, K. M. Shah, D. L. Lath…·A. Gartland
This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.
DOI 10.1016/j.jbo.2021.100398 - Cell BiologybioRxiv
aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis
O. Molinar-Inglis, C. A. Birch, D. Nicholas…·J. Trejo
This study identifies a novel β-arrestin-2-mediated signaling pathway that mediates aPC/PAR1's anti-apoptotic effects in endothelial cells.
DOI 10.1073/pnas.2106623118 - MicrobiologyNutrientsPeer-reviewed
Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate
D. Puengel, A. Treveil, M. J. Dalby…·L. J. Hall
This study shows that Bifidobacterium breve UCC2003 exopolysaccharide (EPS) alters infant microbiota and metabolite profiles by serving as a nutrient substrate.
DOI 10.3390/nu12040948 - MicrobiologybioRxiv
Infant diet promotes Bifidobacterium community cooperation within a single ecosystem
M. A. Lawson, I. J. O'Neill, M. Kujawska…·L. J. Hall
The paper investigates how infant diet influences bifidobacterial community composition and cooperation in the gut, showing resource sharing enhances nutrient utilization and supports Bifidobacterium dominance.
DOI 10.1038/s41396-019-0553-2 - ImmunologybioRxiv
Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response
Y. Uchimura, T. Fuhrer, H. Li…·A. J. Macpherson
The paper develops a model to distinguish microbial and host metabolites using stable isotope tracing and shows that antibodies limit microbial metabolite penetration into host tissues.
DOI 10.1016/j.immuni.2018.08.004