A. Williamson

A role for the ATP-dependent DNA ligase Lig E of Neisseria gonorrhoeae in biofilm formation

This study shows that Lig E in Neisseria gonorrhoeae is non-essential for DNA repair but plays a role in biofilm formation and extracellular DNA joining.

Immunogenic fusion proteins induce neutralizing SARS-CoV-2 antibodies in the serum and milk of sheep

This study shows that immunogenic fusion proteins induce neutralizing SARS-CoV-2 antibodies in sheep serum and milk, with cross-neutralizing activity against variants.

P2RX7 inhibition reduces breast cancer induced osteolytic lesions - implications for bone metastasis

This study shows that inhibiting P2RX7 reduces osteolytic lesions in a murine breast cancer model by increasing cancer cell death and decreasing osteoclast numbers.

Laser-driven Wireless Deep Brain Stimulation using Temporal Interference and Organic Electrolytic Photocapacitors

This paper introduces a wireless deep brain stimulation method using temporal interference and organic photocapacitors, achieving comparable neuronal responses to implanted electrode stimulation.

Organic electrolytic photocapacitors for stimulation of the mouse somatosensory cortex

This paper demonstrates wireless optical stimulation of the mouse somatosensory cortex using organic electrolytic photocapacitors (OEPCs) activated by deep-red light, enabling wireless neural stimulation without external wires or power supplies.

Using the Tea Bag Index to determine how two human pharmaceuticals affect litter decomposition by aquatic microorganisms.

This study uses the Tea Bag Index to show that trimethoprim and EE2 inhibit litter decomposition by aquatic microorganisms through additive effects.

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.

Phospholipid flipping facilitates annexin translocation across membranes

This study identifies phospholipid flipping as essential for annexin translocation from the inner to outer leaflet of the plasma membrane, with TMEM16F playing a key role.