Author

D. Heymann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Astudillo· 1 shared A. Boutin· 1 shared A. Brana· 1 shared A. F. Fernandez· 1 shared A. Gartland· 1 shared A. Kumar· 1 shared A. Miserez· 1 shared A. Rodriguez· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. Astudillo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma

V. Rey, J. Tornin, J. J. Alba-Linares, C. Robledo, D. Murillo, A. Rodriguez, B. Gallego, C. Huergo, A. Brana, A. Astudillo, D. Heymann, A. F. Fernandez, M. F. Fraga, J. Alonso, R. Rodriguez

This study identifies enasidenib as an effective treatment for IDH2 mutant chondrosarcoma through personalized medicine approaches involving sequencing, cell line models, and in vitro/in vivo testing.

eBioMedicine · Apr 1, 2024Peer-reviewedCancer Biology

Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

M.-B. Madel, J. Halper, L. Ibanez, C. Lozano, M. Rouleau, A. Boutin, R. Pontier-Bres, T. Ciucci, M. Topi, C. Hue, J. Amiaud, S. Iborra, D. Sancho, D. Heymann, H.-J. Garchon, , C. Blin-Wakkach

This study identifies PRRs regulating inflammatory osteoclasts and shows that S. boulardii reduces bone loss by targeting these cells.

bioRxiv · Aug 1, 2022Physiology

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

L. Tattersall, K. M. Shah, D. L. Lath, A. Singh, J. M. Down, E. De Marchi, A. Williamson, F. Di Virgilio, D. Heymann, E. Adinolfi, W. D. Fraser, D. Green, M. A. Lawson, A. Gartland

This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.

bioRxiv · May 7, 2021Cancer Biology

Structure of a consensus chitin-binding domain revealed by solution NMR

D. Heymann, H. Mohanram, A. Kumar, C. S. Verma, J. Lescar, A. Miserez

The paper determines the 3D structure of a chitin-binding domain from a squid CBP using NMR, revealing how the R&R motif binds chitin and providing insights for biomimetic material design.

bioRxiv · Jan 8, 2020Biochemistry