Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis
S. Trivedi, D. Labuz, C. P. Anderson, C. V. Araujo, A. Blair, E. Middleton, A. Tran, M. Mulvey, R. Campbell, J. S. Hale, M. T. Rondina, D. T. Leung
This study shows MAIT cells are activated and dysfunctional in sepsis, contributing to protective cytokine responses in experimental sepsis but reduced in clinical cases.
bioRxiv · Feb 5, 2020Physiology