Author

D. Last

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Braga· 2 shared G. Lackner· 2 shared I. Richter· 2 shared M. Hasan· 2 shared C. Beemelmanns· 1 shared C. Hertweck· 1 shared D. Leichnitz· 1 shared F. Schalk· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

D. Braga

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2 papers

Recent·Most cited

Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F420 and its derivative 3PG-F420

M. Hasan, S. Schulze, L. Berndt, G. J. Palm, D. Braga, I. Richter, D. Last, M. Lammers, G. Lackner

This paper identifies amino acids governing substrate specificity in CofC, reveals a labile reaction product, and shows CofD's role in controlling biosynthesis of 3PG-F420.

bioRxiv · Aug 11, 2021Microbiology

Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420

D. Braga, D. Last, M. Hasan, H. Guo, D. Leichnitz, Z. Uzum, I. Richter, F. Schalk, C. Beemelmanns, C. Hertweck, G. Lackner

The paper identifies novel F420 derivatives in Paraburkholderia rhizoxinica, reveals their biosynthesis pathway, and demonstrates their functional activity and potential for biocatalysis.

bioRxiv · Jul 26, 2019Biochemistry