S. Schulze

Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa chain locus in individuals of diverse ancestry

The paper uses long-read sequencing to resolve haplotype variation and genetic architecture in the human IGK locus across diverse ancestries, identifying novel variants and population-specific allele frequencies.

Identification and characterization of structural and regulatory cell-shape determinants in Haloferax volcanii

The paper identifies and characterizes proteins involved in cell-shape determination in Haloferax volcanii using proteomics, genetics, and live-cell imaging.

Advanced understanding of prokaryotic biofilm formation using a cost-effective and versatile multi-panel adhesion (mPAD) mount

The paper introduces a 3D-printed mPAD mount for analyzing biofilm formation under varied conditions and shows phenazines are crucial for anoxic biofilm formation in Pseudomonas aeruginosa.

Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F420 and its derivative 3PG-F420

This paper identifies amino acids governing substrate specificity in CofC, reveals a labile reaction product, and shows CofD's role in controlling biosynthesis of 3PG-F420.

The TIR-NBS-LRR protein CSA1 is required for autoimmune cell death in Arabidopsis pattern recognition co-receptor bak1 and bir3 mutants

The paper identifies CSA1 as a TIR-NBS-LRR protein required for autoimmune cell death in Arabidopsis when BAK1 and BIR3 are mutated, linking BAK1 to NLR proteins in immune responses.

BoolSim, a Graphical Interface for Open Access Boolean Network Simulations and Use in Guard Cell CO2 Signaling

This study presents an open-source graphical interface for Boolean network simulations and applies it to an abscisic acid signaling network in guard cells, incorporating CO2 regulation.

Glycoproteomics of Haloferax volcanii reveals an extensive glycoproteome and concurrence of different N-glycosylation pathways

The paper identifies an extensive N-glycoproteome in Haloferax volcanii and shows that different N-glycosylation pathways can modify the same sites under identical culture conditions.

Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb pattern formation

The allosteric modulation of Complement C5 by knob domain peptides

This study shows that knob domain peptides modulate complement C5 through allosteric mechanisms, revealing new therapeutic inhibitors and introducing knob domains as low molecular weight antibody fragments.

LIPID ANCHORING OF ARCHAEOSORTASE SUBSTRATES AND MID-CELL GROWTH IN HALOARCHAEA

This study identifies a pathway in Haloferax volcanii where ArtA, PssA, and PssD co-localize at the mid-cell to facilitate lipid anchoring of surface proteins and mid-cell growth.

Novel insights into N-glycan fucosylation and core xylosylation in C. reinhardtii

The paper identifies a second core xylosyltransferase (XylT1B) and a fucosyltransferase in C. reinhardtii, showing their roles in N-glycan core modifications through mutant analysis.

Differences in player position running velocity at lactate thresholds among male professional German soccer players

This study compares running velocities at lactate thresholds among different soccer player positions in German professional teams, finding significant differences in performance levels.

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

The paper investigates how oncogenic KRAS and BRAF differentially activate ERK in colon cancer and intestinal epithelium, revealing cell type-specific effects and novel regulatory mechanisms.