Author

G. Lackner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

D. Braga· 3 shared A. P. Graca· 2 shared C. Beemelmanns· 2 shared D. Last· 2 shared H. Guo· 2 shared I. Richter· 2 shared M. Hasan· 2 shared A. Starick· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMicrobiology

D. Braga

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

A. P. Graca, V. Nikitushkin, M. Ellerhorst, C. Vilhena, T. Klassert, A. Starick, M. Siemers, W. K. Al-Jammal, I. Vilotijevic, H. Slevogt, K. Papenfort, G. Lackner

This study identifies MftG as a mycofactocin dehydrogenase essential for ethanol metabolism in mycobacteria by linking mycofactocin oxidation to respiration.

bioRxiv · Mar 26, 2024Microbiology

Diversification by CofC and control by CofD govern biosynthesis and evolution of coenzyme F420 and its derivative 3PG-F420

M. Hasan, S. Schulze, L. Berndt, G. J. Palm, D. Braga, I. Richter, D. Last, M. Lammers, G. Lackner

This paper identifies amino acids governing substrate specificity in CofC, reveals a labile reaction product, and shows CofD's role in controlling biosynthesis of 3PG-F420.

bioRxiv · Aug 11, 2021Microbiology

Biosynthesis of the redox cofactor mycofactocin comprises oligoglycosylation by MftF in Mycolicibacterium smegmatis

L. Pena-Ortiz, A. P. Graca, H. Guo, D. Braga, T. Köllner, L. Regestein, C. Beemelmanns, G. Lackner

This study identifies mycofactocin (MFT) as a redox cofactor in Mycolicibacterium smegmatis, reveals its oligoglycosylation by MftF, and confirms its role in ethanol metabolism.

bioRxiv · Oct 29, 2019Microbiology

Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420

D. Braga, D. Last, M. Hasan, H. Guo, D. Leichnitz, Z. Uzum, I. Richter, F. Schalk, C. Beemelmanns, C. Hertweck, G. Lackner

The paper identifies novel F420 derivatives in Paraburkholderia rhizoxinica, reveals their biosynthesis pathway, and demonstrates their functional activity and potential for biocatalysis.

bioRxiv · Jul 26, 2019Biochemistry