Author

D. Latek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:deep learning· 2 Assay:structural biology· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

P. Dragan· 2 shared A. Atzei· 1 shared A. Gonzalez· 1 shared A. Makal· 1 shared A. Morales-Pastor· 1 shared A. Sztyler· 1 shared A. Varela-Rial· 1 shared B. Medel Lacruz· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

P. Dragan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Keras/TensorFlow in Drug Design for Immunity Disorders

P. Dragan, K. Joshi, A. Atzei, D. Latek

This study uses Keras/TensorFlow to enhance structure-based virtual screening for drug discovery targeting chemokine receptors, showing improved prediction of receptor subtype selectivity.

bioRxiv · Sep 14, 2023 · PreprintImmunology

Helix 8 in chemotactic receptors of the complement system.

S. Wisniewski, P. Dragan, A. Makal, D. Latek

The paper analyzes the structural and dynamic properties of C5aR1, a chemotactic receptor, focusing on the role of inverted helix H8 in its activation mechanism and signaling differences compared to its homolog C5aR2.

bioRxiv · Mar 7, 2022Immunology

GPCRmd uncovers the dynamics of the 3D-GPCRome

I. Rodriguez-Espigares, M. Torrens-Fontanals, J. K. S. Tiemann, D. Aranda-Garcia, J. M. Ramirez-Anguita, T. M. Stepniewski, N. Worp, A. Varela-Rial, A. Morales-Pastor, B. Medel Lacruz, G. Pandy-Szekeres, E. Mayol, T. Giorgino, J. Carlsson, X. Deupi, , Wein

GPCRmd provides an online platform for visualizing and analyzing GPCR molecular dynamics simulations, demonstrating its utility through analyses of internal water networks and sodium ion interactions.

Nature Methods · Jul 13, 2020Peer-reviewedBiophysics