Harnessing patient-specific response dynamics to optimize evolutionary therapies for metastatic clear cell renal cell carcinoma - Learning to adapt
I. C. Sorribes, A. Basu, R. Brady, P. M. Enriquez-Navas, X. Feng, J. N. Kather, N. Nerlakanti, R. Stephens, M. Strobl, I. Tavassoly, N. Vitos, D. Lemanne, B. Manley, C. O'Farrelly, H. Enderling
This paper develops a dynamic tumor-immune model to predict patient response to treatment using NLR as a biomarker and simulates optimal therapies for virtual RCC patients.
bioRxiv · Feb 28, 2019 · PreprintCancer Biology