RNA-binding protein Orb2 causes microcephaly and supports centrosome asymmetry in Drosophila neural stem cells
B. V. Robinson, J. Buehler, T. Hailstock, T. H. Adebambo, J. Fang, D. S. Mehta, D. Lerit
This study shows Orb2 supports centrosome asymmetry in Drosophila NSCs, leading to microcephaly when lost, and identifies a conserved role for CPEB proteins in centrosome regulation.
bioRxiv · Nov 23, 2021 · PreprintCell Biology