Cell BiologybioRxiv
IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1beta secretion
A. Dinarello, M. May, J. Amo-Aparicio…·C. A. Dinarello
This paper shows IL-38 promotes intestinal stem cell growth by enhancing WNT signaling and beneficial IL-1beta secretion, while also having anti-inflammatory effects in the small intestine.
DOI 10.1073/pnas.2306476120