BiochemistrybioRxiv
Defining the Substrate Envelope of SARS-CoV-2 Main Protease to Predict and Avoid Drug Resistance
A. M. Shaqra, S. Zvornicanin, Q. Y. Huang…·C. A. Schiffer
This study defines the substrate envelope of SARS-CoV-2 main protease using cocrystal structures to identify vulnerable sites that may lead to drug resistance.
DOI 10.1038/s41467-022-31210-w