Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
F. C. Cassidy, N. Kedia-Mehta, R. Bergin, A. Woodcock, A. Berisha, B. M. Bradley, E. Booth, O. K. Ryan, L. V. Sinclair, D. O'Shea, A. E. Hogan
This study shows glycogen metabolism supports rapid MAIT cell cytotoxicity and cytokine production, which may enhance their use in immunotherapy.
bioRxiv · Dec 20, 2022Immunology
C. Gallagher, J. MacMahon, C. O'Neill, F. C. Cassidy, H. Dunbar, C. DeBarra, C. Cadden, M. M. Pisarska, N. A. Wood, J. C. Masterson, E. N. McNamee, K. English, D. O'Shea, A.-M. Tobin, A. E. Hogan
This study shows MAIT cells are altered in Hidradenitis Suppurativa patients, with reduced frequencies and IL-17 bias, and highlights RORyt inhibition as a potential therapy.
bioRxiv · Jan 17, 2022Immunology
N. Kedia-Mehta, M. M. Pisarska, C. Rollings, C. O'Neill, C. DeBarra, C. Foley, N. A. Wood, N. Wrigley-Kelly, N. Veerapen, G. E. Besra, R. Bergin, N. Jones, D. O'Shea, L. V. Sinclair, A. E. Hogan
This study identifies a MYC-SLC7A5-Glycolysis metabolic axis critical for MAIT cell proliferation, showing its impairment in obesity.
bioRxiv · Jan 17, 2022 · PreprintImmunology
Z. He, C. Charleton, R. Devine, M. Kelada, J. M. D. Walsh, G. Conway, S. Gunes, J. R. M. Mondala, F. Tian, B. Tiwari, G. K. Kinsella, R. Malone, D. O'Shea, M. Devereux, W. Wang, , J. F. Curtin
The paper tests the synergistic anti-cancer effects of pyrazolopyrimidinones combined with cold atmospheric plasma against glioblastoma cells and identifies two prodrugs that show enhanced cytotoxicity in combination.
bioRxiv · Feb 4, 2021Cancer Biology
E. A. Lusi, I. Santino, A. Petrucca, V. Zollo, F. Magri, D. O'Shea, A. Tammaro
The paper investigates the relationship between nickel-resistant gut bacteria, nickel allergy, and overweight in women by analyzing stool samples from allergic and non-allergic individuals.
bioRxiv · Feb 11, 2019 · PreprintMicrobiology