Author

R. Devine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:genetic perturbation / CRISPR· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. I. Hutchings· 2 shared Z. Qin· 2 shared B. I. Wilkinson· 1 shared B. K. Moriarity· 1 shared B. Tiwari· 1 shared B. Wilkinson· 1 shared C. Arnold· 1 shared C. Charleton· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

M. I. Hutchings

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CRISPR-Targeted CAR Gene Insertion Using Cas9/RNP and AAV6 Enhances Anti-AML Activity of Primary NK Cells

M. Naeimi Kararoudi, S. Likhite, E. Elmas, K. Yamamoto, M. Schwartz, K. Sorathia, M. Pereira, R. Devine, J. Lyberger, G. K. Behbehani, N. Chakravarti, B. K. Moriarity, K. Meyer, D. A. Lee

bioRxiv · Mar 17, 2021 · PreprintImmunology

Synergistic Cytotoxicity Between Cold Atmospheric Plasma and Pyrazolopyrimidinones Against Glioblastoma Cells

Z. He, C. Charleton, R. Devine, M. Kelada, J. M. D. Walsh, G. Conway, S. Gunes, J. R. M. Mondala, F. Tian, B. Tiwari, G. K. Kinsella, R. Malone, D. O'Shea, M. Devereux, W. Wang, , J. F. Curtin

The paper tests the synergistic anti-cancer effects of pyrazolopyrimidinones combined with cold atmospheric plasma against glioblastoma cells and identifies two prodrugs that show enhanced cytotoxicity in combination.

bioRxiv · Feb 4, 2021Cancer Biology

Refactoring the formicamycin biosynthetic gene cluster to make high-level producing strains and new molecules

R. Devine, H. McDonald, Z. Qin, C. Arnold, K. Noble, G. Chandra, B. I. Wilkinson, M. I. Hutchings

This paper refactors the formicamycin biosynthetic gene cluster to enhance production and generate new molecules by manipulating regulatory elements.

bioRxiv · Sep 15, 2020 · PreprintMicrobiology

Aromatic polyketide biosynthesis: fidelity, evolution and engineering

Z. Qin, R. Devine, M. I. Hutchings, B. Wilkinson

The paper reports new aromatic polyketides called formicapyridines, shows how mutating a single gene increases their production, and identifies a non-catalytic role for ABM superfamily proteins in maintaining biosynthetic pathway fidelity.

bioRxiv · Mar 18, 2019 · PreprintBioengineering