C. Gallagher

Mucosal associated invariant T cells are altered in patients with Hidradenitis Suppurativa and contribute to the inflammatory milieu

This study shows MAIT cells are altered in Hidradenitis Suppurativa patients, with reduced frequencies and IL-17 bias, and highlights RORyt inhibition as a potential therapy.

Replication Study: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

This replication study confirms some findings of the original study on RAF inhibitors and their effects on MAPK pathway activation but reports discrepancies in key experiments.

The Forget-Me-Not dHCP study: 7 Tesla high resolution diffusion imaging in the unfixed post-mortem neonatal brain

The paper describes the Forget-Me-Not dHCP study, which acquires high-resolution diffusion MRI data from unfixed post-mortem neonatal brains and presents preliminary analyses of cortical and white matter structures.

Among-individual diet variation within a lake trout ecotype: lack of stability of niche use.

The paper examines diet variation among lake trout within an ecotype, finding that individual trophic specialization occurs despite lack of genetic or morphological differentiation.

Dietary vs non-dietary fatty acid profiles of lake trout ecotypes from Lake Superior and Great Bear Lake: Are fish really what they eat?

The paper examines non-dietary fatty acid profiles in lake trout ecotypes to assess their ability to distinguish intraspecific diversity across lakes and ecotypes.

Sub physiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells

This study shows that reducing temperature induces widespread alternative splicing in CHO cells, with many events occurring in genes not detected by standard expression analysis.

Expanding the Chinese hamster ovary cell long non-coding RNA transcriptome using RNASeq

This study expands the long non-coding RNA (lncRNA) transcriptome of Chinese hamster ovary (CHO) cells using RNASeq, doubling annotated lncRNA transcripts and identifying 1,000 new antisense lncRNAs.

Acetazolamide reduces exercise capacity following a five-day ascent to 4559 m on Monte Rosa

This study shows that acetazolamide reduces exercise capacity at high altitude, with greater effects in older individuals.