Aerosolized TLR Agonists Suppress Acute Sendai Virus Lung Infection and Chronic Airway Disease in Mice
D. L. Goldblatt, J. R. Flores, G. Valverde Ha, A. M. Jaramillo, S. Tkachman, C. K. Kirkpatrick, S. Wali, B. Hernandez, D. Ost, B. Scott, J. Chen, S. E. Evans, M. Tuvim, B. F. Dickey
The paper shows that aerosolized TLR agonists reduce Sendai virus lung burden and chronic asthma-like disease in mice by suppressing inflammation and IL-33 production.
bioRxiv · Jun 13, 2019 · PreprintImmunology