FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction
J. L. Diener, S. Mowbray, D. Yowe, J. Xu, S. Caplan, A. Misra, A. Kapur, W.-J. Huang, J. Shapiro, X. Ke, X. Wu, A. Bose, D. Panza, M. Chen, V. Beaulieu, J. Gao
This study shows that FGF21-PEG normalizes plasma glucose in two mouse diabetes models, even when insulin receptor function is impaired.
bioRxiv · Jan 4, 2021Pharmacology & Toxicology