Author

D. Patterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:metabolomics· 2

Frequent Co-Authors

G. N. Vacano· 3 shared N. Duval· 3 shared T. G. Wilkinson· 3 shared M. Zikanova· 2 shared R. C. Mazzarino· 2 shared V. Baresova· 2 shared A. D. Gottscho· 1 shared A. Gupta· 1 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

G. N. Vacano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling

M. F. Oliveira, J. P. Romero, M. Chung, S. Williams, A. D. Gottscho, A. Gupta, S. E. Pilipauskas, S. Mohabbat, N. Raman, D. Sukovich, D. Patterson, Visium HD Development Team, S. E. B. Taylor

This study uses Visium HD spatial transcriptomics to map immune cell populations in colorectal cancer tumor microenvironments, identifying spatially distinct macrophage and T cell subpopulations.

bioRxiv · Jun 4, 2024 · PreprintCancer Biology

Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity

R. C. Mazzarino, V. Baresova, M. Zikanova, N. Duval, T. G. Wilkinson, D. Patterson, G. N. Vacano

The paper analyzes transcriptome and metabolome changes in a GART-null HeLa cell line under different purine conditions, identifying altered CD36 expression and potential links to neurodegenerative diseases.

bioRxiv · Jun 23, 2020 · PreprintCell Biology

Reduced purine biosynthesis in humans after their divergence from Neandertals

V. Stepanova, K. E. Moczulska, G. N. Vacano, X.-c. Ju, S. Riesenberg, D. Macak, T. Maricic, L. Dombrowski, M. Schörnig, K. Anastassiadis, O. Baker, R. Naumann, E. E. Khrameeva, A. Vanyushkina, E. Stekolschikova, , S. Pääbo

The paper compares metabolomes across humans, chimpanzees, and macaques to identify reduced purine biosynthesis in humans, linked to an amino acid substitution in adenylosuccinate lyase.

bioRxiv · May 11, 2020Evolutionary Biology

The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model for ATIC deficiency and ZMP accumulation

R. C. Mazzarino, V. Baresova, M. Zikanova, N. Duval, T. G. Wilkinson, D. Patterson, G. N. Vacano

The paper characterizes the transcriptome of a CRISPR-Cas9-generated ATIC-null HeLa cell line under purine-supplemented and depleted conditions, identifying gene expression changes related to Alzheimer's disease and other biological processes.

bioRxiv · Apr 28, 2020Cell Biology

Copyright and the Use of Images as Biodiversity Data

W. Egloff, D. Agosti, P. Kishor, D. Patterson, J. A. Miller

The paper examines copyright and reuse of images in taxonomic literature, concluding that most images lack copyright protection due to standardized presentation and lack of creativity.

bioRxiv · Nov 11, 2016Scientific Communication & Education