Correlative three-dimensional super-resolution and block face electron microscopy of whole vitreously frozen cells
D. P. Hoffman, G. Shtengel, C. S. Xu, K. R. Campbell, M. Freeman, L. Wang, D. E. Milkie, H. A. Pasolli, N. Iyer, J. A. Bogovic, D. R. Stabley, A. Shirinifard, S. Pang, D. Peale, K. Schaefer, , H. F. Hess
This study develops a platform for 3D correlative cryogenic super-resolution and block-face EM of whole vitreously frozen cells, revealing new protein-ultrastructure relationships.
bioRxiv · Sep 18, 2019Cell Biology