D. Plaskon

Kinetic-Mechanistic Evidence for Which E. coli RNA Polymerase-{lambda}PR Open Promoter Complex Initiates and for Stepwise Disruption of Contacts in Bubble Collapse

This paper investigates the kinetic mechanism of RNA polymerase initiation at the λPR promoter, identifying stepwise disruption of contacts and temperature-dependent changes in initiation dynamics.

Fluorescence-Detected Conformational Changes in Duplex DNA in Open Complex Formation by E. coli RNA Polymerase: Upstream Wrapping and Downstream Bending Precede Clamp Opening and Insertion of the Downstream Duplex

This study uses FRET and PIFE to analyze DNA conformational changes during E. coli RNA polymerase open complex formation, revealing upstream wrapping and downstream bending before clamp opening.