BioengineeringFrontiers in PhysiologyPeer-reviewed
Enhanced intrathecal drug dispersion achieved by high volume injection and natural micromixing
A. O. Ayansiji, D. S. Gehrke, B. Baralle…·A. A. Linninger
This study demonstrates that high-volume intrathecal injections enhance drug dispersion throughout the spinal subarachnoid space by leveraging natural CSF oscillations and micro-mixing.