Author

D. Saintillan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 6

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:Hi-C· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

P. Rangamani· 3 shared A. Mahajan· 2 shared A. Mahapatra· 2 shared A. Zidovska· 2 shared M. J. Shelley· 2 shared B. Chakrabarti· 1 shared C. Li· 1 shared P. Castilla· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiophysics

P. Rangamani

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Author profile →

6 papers

Recent·Most cited

Cell motility modes are selected by the interplay of mechanosensitive adhesion and membrane tension

Y. Chen, D. Saintillan, P. Rangamani

This paper extends a 1D model of cell motility to 2D, showing that the interplay between mechanosensitive adhesions and membrane tension can lead to different motility modes like gliding and zigzagging.

bioRxiv · May 31, 2023 · PreprintBiophysics

A chemomechanical model of sperm locomotion reveals two modes of swimming

C. Li, B. Chakrabarti, P. Castilla, A. Mahajan, D. Saintillan

This study presents a chemomechanical model of sperm swimming that identifies two distinct modes of locomotion with different waveforms and velocity patterns based on dynein activity.

bioRxiv · Apr 10, 2022Biophysics

Euchromatin activity enhances segregation and compaction of heterochromatin in the cell nucleus

A. Mahajan, W. Yan, A. Zidovska, D. Saintillan, M. J. Shelley

This study models nuclear chromatin organization using active Zimm chains to show how euchromatin activity drives heterochromatin segregation and compaction through hydrodynamic interactions and crosslinking.

bioRxiv · Feb 22, 2022Biophysics

Curvature-driven feedback on aggregation-diffusion of proteins in lipid bilayers

A. Mahapatra, D. Saintillan, P. Rangamani

The paper develops a model that couples protein aggregation, diffusion, and membrane curvature to predict pattern formation on lipid bilayers.

bioRxiv · Apr 2, 2021Biophysics

Transport Phenomena in Fluid Films with Curvature Elasticity

A. Mahapatra, D. Saintillan, P. Rangamani

The paper develops a theoretical framework coupling lipid flow, protein diffusion, and membrane curvature elasticity to study membrane dynamics.

Journal of Fluid Mechanics · Oct 23, 2020Peer-reviewedBiophysics

Extensile motor activity drives coherent motions in a model of interphase chromatin

D. Saintillan, M. J. Shelley, A. Zidovska

This study develops a model of interphase chromatin using active-polymer dynamics to explain coherent motions observed in experiments.

bioRxiv · May 10, 2018Biophysics