Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
N. L. Truex, S. Mohapatra, M. Melo, J. Rodriguez, N. Li, W. Abraham, D. Sementa, F. Touti, D. B. Keskin, C. J. Wu, D. J. Irvine, R. Gomez-Bombarelli, B. L. Pentelute
This paper uses machine learning to design cytotoxic T cell epitopes by modeling proteasomal degradation scores and testing their immunogenicity.
bioRxiv · Aug 22, 2023 · PreprintImmunology