Author

D. Siekhaus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. Gyoergy· 3 shared M. Akhmanova· 2 shared M. Roblek· 2 shared S. Emtenani· 2 shared A. Akopian· 1 shared A. Ratheesh· 1 shared B. Szulc· 1 shared D. Krueger· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

A. Gyoergy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The solute carrier MFSD1 decreases β1 integrins activation status and thus tumor metastasis

M. Roblek, J. Bicher, M. van Gogh, A. Gyoergy, R. Seeboeck, B. Szulc, M. Damme, M. Olczak, L. Borsig, D. Siekhaus

This study shows that MFSD1 reduces β1 integrin activation, thereby suppressing tumor metastasis in a mouse model.

bioRxiv · Sep 17, 2021Cancer Biology

Cell division in tissues enables macrophage infiltration

M. Akhmanova, A. Gyoergy, M. Vlasov, F. Vlasov, D. Krueger, A. Akopian, S. Emtenani, A. Ratheesh, S. De Renzis, D. Siekhaus

The paper shows that cell division in Drosophila embryos enables macrophage invasion by disassembling focal adhesions, allowing nuclear movement and tissue penetration.

bioRxiv · Apr 19, 2021Cell Biology

Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance

V. Belyaeva, S. Wachner, A. Gyoergy, S. Emtenani, I. Gridchyn, M. Akhmanova, M. Linder, M. Roblek, M. Sibilia, D. Siekhaus

This study identifies Drosophila Fos as a regulator of cortical actin dynamics in macrophages, enabling tissue infiltration by counteracting tissue resistance.

bioRxiv · Sep 18, 2020Cell Biology