Tuft cells act as regenerative stem cells in the human intestine
L. Huang, J. H. Bernink, A. Giladi, D. Krueger, G. J. F. van Son, M. H. Geurts, G. Busslinger, L. Lin, M. Zandvliet, P. J. Peters, C. Lopez-Iglesias, C. J. Buskens, W. A. Bemelman, H. Begthel, H. Clevers
The paper identifies four human tuft cell states, showing they function as radiation-resistant stem cells capable of regenerating the intestinal epithelium.
bioRxiv · Mar 17, 2024Cell Biology