Author

D. Siemes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

D. R. Engel· 2 shared P. Spangenberg· 2 shared B. Siebels· 1 shared C. Krisp· 1 shared D. Führer· 1 shared D. Geist· 1 shared E. Tolstik· 1 shared F. Wagenlehner· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

D. R. Engel

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2 papers

Recent·Most cited

Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice

D. Geist, G. S. Hönes, S. C. Grund, J. Pape, D. Siemes, P. Spangenberg, E. Tolstik, S. Dörr, N. Spielmann, H. Fuchs, V. Gailus-Durner, M. Hrabe de Angelis, J. Mittag, D. R. Engel, D. Führer, , L. C. Moeller

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.

bioRxiv · Nov 24, 2023Physiology

Proteomic adaptations in the kidney reveal orchestration of local and secreted antimicrobial peptides in human pyelonephritis

L. Borgards, B. Siebels, H. Voss, C. Krisp, J. Schmitz, L. Schwarz, D. Siemes, P. Spangenberg, J. H. Braesen, S. von Vietinghoff, H. Schluter, F. Wagenlehner, D. R. Engel, O. Shevchuk

This study identifies proteomic adaptations in human pyelonephritis, revealing elevated antimicrobial peptides and their potential protective role against systemic inflammation.

bioRxiv · Sep 14, 2023 · PreprintImmunology