V. Gailus-Durner

The paper identifies weaning body weight as a key predictor of adult diabetes in TALLYHO/JngJ mice, highlighting its relevance to childhood obesity research.

This study compares TRα and TRβ knockout mice with DNA-binding-deficient mutants to show noncanonical TR signaling contributes to physiological functions beyond canonical genomic pathways.

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.

This study shows TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity, linking it to mechanotransduction and breast cancer initiation.

This paper describes a new mouse model with a KIT mutation that develops late-onset mammary tumors with high penetrance and lung metastasis.

This study examines a mouse model of methylmalonic aciduria, finding reduced energy expenditure, altered metabolism, and metabolic inflexibility.

The study characterizes the Titan mouse as a model for metabolically unhealthy obesity and shows that dietary intervention improves its health and extends lifespan.