Macrophages can inhibit and enhance endometriosis depending on their origin
C. Hogg, P. Dhami, M. Rosser, M. Mack, D. Soong, J. W. Pollard, S. J. Jenkins, A. W. Horne, E. Greaves
This study shows that macrophages in endometriosis lesions can either promote or suppress disease depending on their origin, with eutopic endometrial macrophages being pro-endometriosis and recruited monocyte-derived macrophages being anti-endometriosis.
bioRxiv · Apr 30, 2020Immunology