J. W. Pollard

This study shows that IL4 signaling in macrophages promotes lung metastasis by enhancing tumor cell extravasation and regulating pro-tumoral gene expression.

This study shows that mammary cancer in mice increases circulating and splenic monocytes without altering their ratios or half-lives, but changes their transcriptome, particularly in the bone marrow and blood, with differences from human breast cancer.

This study shows that macrophages in endometriosis lesions can either promote or suppress disease depending on their origin, with eutopic endometrial macrophages being pro-endometriosis and recruited monocyte-derived macrophages being anti-endometriosis.

This study shows that Cx3cr1 mRNA expression differs between circulating monocytic subsets in humans but not in mice.

This study uses single-cell transcriptomics to identify novel fibrotic cell types and interactions in human liver cirrhosis, revealing potential therapeutic targets.