Author

D. Spiegelberg

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Chandramohan· 1 shared A. Peier· 1 shared A. W. Partridge· 1 shared B. Henry· 1 shared B. Sherborne· 1 shared C. J. Brown· 1 shared C. S. Verma· 1 shared C. W. Johannes· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiochemistry

A. Chandramohan

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintFeb 25, 2023

Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application toMdm2/X dual antagonists

A. Chandramohan, H. Josien, T. Yuen…·A. W. Partridge

The paper develops design rules for stapled alpha-helical peptides to improve in vivo activity and reduce off-target effects, demonstrating significant improvements in potency and safety.

DOI 10.1101/2023.02.25.530030

experimental assaydrug response / drug discovery

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