Author

D. Tedesco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:chicken / avian· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

M. Zaffagnini· 3 shared M. Meloni· 2 shared P. Trost· 2 shared S. D. Lemaire· 2 shared S. Fermani· 2 shared A. Cingolani· 1 shared A. D. Singhi· 1 shared A. Grakoui· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiochemistry

M. Zaffagnini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease

S. Chaudhary, R. P. Rai, P. B. Pal, D. Tedesco, A. D. Singhi, S. P. Monga, A. Grakoui, S. S. Iyer, R. Raeman

This study shows that a western diet impairs T regulatory cell function in NAFLD, leading to chronic inflammation and fibrosis, and suggests restoring Treg function as a potential therapy.

bioRxiv · Mar 23, 2023 · PreprintPathology

Structural and functional characterization of chloroplast ribulose-5-phosphate-3-epimerase from the model green microalga Chlamydomonas reinhardtii

M. Meloni, S. Fanti, D. Tedesco, L. Gurrieri, P. Trost, S. Fermani, S. D. Lemaire, M. Zaffagnini, J. Henri

This study characterizes the structural and functional properties of CrRPE1, an enzyme in the Calvin-Benson-Bassham cycle of Chlamydomonas reinhardtii, revealing its catalytic behavior and regulatory mechanisms.

bioRxiv · Sep 29, 2022 · PreprintBiochemistry

Application of the SMALP technology to the isolation of GPCRs from low-yielding cell lines

D. Tedesco, M. Maj, P. Malarczyk, A. Cingolani, M. Zaffagnini, A. Wnorowski, T. Benelli, R. Mazzoni, M. Bartolini, K. Jozwiak

This paper optimizes SMALP protocols to improve GPCR isolation from low-yielding human cell lines by adjusting ionic strength and combining chromatography techniques.

bioRxiv · Jan 26, 2021Biophysics

Structural and functional insights into nitrosoglutathione reductase from Chlamydomonas reinhardtii

A. Tagliani, J. Rossi, C. H. Marchand, M. de Mia, D. Tedesco, G. Libero, M. Meloni, G. Falini, P. Trost, S. D. Lemaire, S. Fermani, M. Zaffagnini

The paper characterizes CrGSNOR1 from Chlamydomonas reinhardtii, revealing its strict specificity for GSNO and NADH, conserved 3D structure, and resistance to thiol-based redox modifications.

bioRxiv · Aug 31, 2020Plant Biology