Age-related changes in human skeletal muscle transcriptome and proteome are moreaffected by chronic inflammation and physical inactivity than primary aging
N. S. Kurochkina, M. A. Orlova, M. A. Vigovskiy…·D. V. Popov
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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
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N. S. Kurochkina, M. A. Orlova, M. A. Vigovskiy…·D. V. Popov
P. A. Makhnovskii, I. V. Kukushkina, N. S. Kurochkina, D. V. Popov
This study shows that knocking out six Hsp70 genes in Drosophila reduces locomotor speed and disrupts adaptation to exercise training, with changes in leg muscle gene expression.
D. C. Turner, P. P. Gorski, M. F. Maasar…·A. P. Sharples
This study identifies age-related hypermethylation in HOX genes in aged human skeletal muscle and stem cells, with physical activity inversely affecting methylation in some genes.
R. A. Seaborne, D. C. Hughes, D. C. Turner…·A. P. Sharples
This paper identifies UBR5 as a novel E3 ubiquitin ligase inversely regulated to MuRF1/MAFbx, epigenetically modulated during skeletal muscle recovery from atrophy and hypertrophy, and genetically associated with muscle fiber size and strength traits.