Intra-tumor heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumor interfaces
S. Sangaletti, F. Iannelli, F. Zanardi, V. Cancila, P. Portararo, L. Botti, D. Vacca, C. Chiodoni, A. Di Napoli, C. Valenti, M. C. Vegliante, F. Pisati, A. Gulino, M. Ponzoni, M. P. Colombo, C. Tripodo
This study investigates how stromal adaptations in the tumor microenvironment contribute to intra-tumor heterogeneity in DLBCL, showing their impact on transcriptional programs and MYC expression.
EBioMedicine · Nov 1, 2020Peer-reviewedCancer Biology