F. Iannelli

SP2G identifies invasive glioblastoma sub-populations through an in vivo mimicry platform and imaging analysis, revealing intra-patient heterogeneity in cell motility.

This paper demonstrates that the prophage phi1207.3 from Streptococcus pyogenes can produce mature phage particles and lysogenize different Streptococci, but lacks sufficient lytic activity to form plaques.

This study identifies Gpr126 as a regulator of BBB development and shows its detrimental role in ischemic stroke, with potential therapeutic implications.

The paper identifies PIP4K2B as a mechanosensor that induces nuclear softening via UHRF1, affecting YAP activity and cell motility in cancer.

The paper develops 3D organoid cultures using decellularized ECM from colorectal peritoneal metastases to model the metastatic niche and assess chemotherapy response.

This study shows that aging-related telomere shortening and DNA damage response increase ACE2 expression, making elderly individuals more susceptible to SARS-CoV-2 infection.

This study investigates how stromal adaptations in the tumor microenvironment contribute to intra-tumor heterogeneity in DLBCL, showing their impact on transcriptional programs and MYC expression.