Cell BiologybioRxiv
DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging
S. Sepe, F. Rossiello, V. Cancila…·F. d'Adda di Fagagna
This study shows that aging-related telomere shortening and DNA damage response increase ACE2 expression, making elderly individuals more susceptible to SARS-CoV-2 infection.