Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
B. Bassani, G. Simonetti, V. Cancila, M. Ciciarello, A. Piva, C. Chiodoni, D. Lecis, A. Gulino, E. Fonzi, L. Botti, P. Portararo, M. Costanza, J. Schwaller, A. Tzankov, M. Ponzoni, , S. Sangaletti
This study shows ZEB1 in AML suppresses CD8 T-cells and promotes Th17 cells, contributing to immune suppression and tumor progression.
bioRxiv · Jul 8, 2023Immunology
L. Menin, J. Weber, S. Villa, E. Martini, E. Maspero, V. Cancila, P. Maiuri, A. Palamidessi, E. Frittoli, F. Bianchi, C. Tripodo, K. Walters, F. Giavazzi, G. Scita, S. Polo
The paper identifies a MYO6-DOCK7-RAC1 axis that restricts RAC1 activity in a planar polarized manner to drive tissue fluidification and collective motion in carcinoma cell monolayers.
bioRxiv · Jan 23, 2023Cell Biology
S. Sepe, F. Rossiello, V. Cancila, F. Iannelli, V. Matti, G. Cicio, M. Cabrini, E. Marinelli, B. Alabi, A. di Lillo, A. Di Napoli, J. W. Shay, C. Tripodo, F. d'Adda di Fagagna
This study shows that aging-related telomere shortening and DNA damage response increase ACE2 expression, making elderly individuals more susceptible to SARS-CoV-2 infection.
bioRxiv · Jun 9, 2021Cell Biology
C. Tripodo, B. Bassani, E. Jachetti, V. Cancila, C. Chiodoni, P. Portararo, L. Botti, C. Vaenti, M. Perrone, M. Ponzoni, P. Comoli, A. Curti, M. P. Colombo, S. Sangaletti
This study demonstrates that neutrophil extracellular traps (NETs) loaded with mutant NPMc+ can be used as a vaccine to treat NPMc-driven myeloproliferation by inducing CD8+ T cell responses and reducing leukemic expansion.
bioRxiv · May 19, 2021Immunology
S. Sangaletti, F. Iannelli, F. Zanardi, V. Cancila, P. Portararo, L. Botti, D. Vacca, C. Chiodoni, A. Di Napoli, C. Valenti, M. C. Vegliante, F. Pisati, A. Gulino, M. Ponzoni, M. P. Colombo, C. Tripodo
This study investigates how stromal adaptations in the tumor microenvironment contribute to intra-tumor heterogeneity in DLBCL, showing their impact on transcriptional programs and MYC expression.
EBioMedicine · Nov 1, 2020Peer-reviewedCancer Biology
G. Bertolini, V. Cancila, M. Milione, G. Lo Russo, O. Fortunato, N. Zaffaroni, M. Tortoreto, G. Centonze, C. Chiodoni, F. Facchinetti, F. Giovinazzo, M. Moro, C. Camisaschi, A. De Toma, C. D'Alterio, , L. Roz
This study shows that cisplatin promotes metastasis by creating pro-metastatic niches, which can be blocked by CXCR4 inhibition.
bioRxiv · Oct 26, 2020Cancer Biology
L. Simula, V. Cancila, Y. Antonucci, A. Colamatteo, C. Procaccini, G. Matarese, C. Tripodo, S. Campello
This study shows PD-1 signalling reduces Drp1 activity in tumor-infiltrating T cells, leading to mitochondrial fusion and impaired T cell function.
bioRxiv · Jul 14, 2020Immunology
G. Nader, S. Aguera-Gonzalez, F. Routet, M. Gratia, M. Maurin, V. Cancila, C. Cadart, M. Gentili, A. Yamada, C. Lodillinsky, E. Lagoutte, C. Villard, J.-L. Viovy, C. Tripodo, G. Scita, , M. Piel
The paper shows that mechanical nuclear envelope ruptures in cancer cells cause DNA damage and promote invasion through ATM activation and TREX1 depletion.
bioRxiv · May 22, 2020Cell Biology
S. Atashpaz, S. Samadi Shams, J. M. Gonzalez, E. Sebestyen, N. Arghavanifard, A. Gnocchi, E. Albers, S. Minardi, G. Faga, P. Soffientini, E. Allievi, V. Cancila, A. Bachi, O. Fernandez-Capetillo, C. Tripodo, , V. Costanzo
This study identifies an ATR-CHK1 pathway in ESCs that enhances fate potential by inducing 2C-like gene expression in response to replication stress.
bioRxiv · Jan 1, 2020Cell Biology