WNT11 is a novel ligand for ROR2 in human breast cancer
K. Menck, S. Heinrichs, D. Wlochowitz, M. Sitte, H. Noeding, A. Janshoff, H. Treiber, T. Ruhwedel, B. Schatlo, C. von der Brelie, S. Wiemann, T. Pukrop, T. Beissbarth, C. Binder, A. Bleckmann
The paper identifies WNT11 as a novel ligand for ROR2 in breast cancer, showing it promotes invasion through RHO/ROCK signaling and forms an auto-stimulatory loop.
Journal of Experimental & Clinical Cancer Research · Dec 15, 2021Peer-reviewedCancer Biology