Author

D.-H. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. C. Newton· 1 shared A. Carfi· 1 shared A. G. Johnson· 1 shared A. M. Arvin· 1 shared A. N. Petrov· 1 shared A. P. Kornev· 1 shared A. Prabhakar· 1 shared A. R. Dunn· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

A. C. Newton

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protein Kinase C gamma Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

C. A. Pilo, T. R. Baffi, A. P. Kornev, M. T. Kunkel, M. Malfavon, D.-H. Chen, L.-C. Huang, C. Longman, N. A. Kannan, W. H. Raskind, D. J. Gonzalez, S. S. Taylor, G. Gorrie, A. C. Newton

SCA14 driver mutations in PKCγ impair autoinhibition, with defect correlating inversely with age of disease onset.

bioRxiv · Jun 24, 2021 · PreprintBiochemistry

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.

S. L. Oliver, Y. Xing, D.-H. Chen, S. H. Roh, G. D. Pintilie, D. A. Bushnell, M. H. Sommer, E. Yang, A. Carfi, W. Chiu, A. M. Arvin

This study identifies the N-terminus of VZV glycoprotein B as critical for membrane fusion, showing that mutations in this region impair viral propagation.

bioRxiv · Sep 8, 2020Microbiology

Limited Dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction

W. Kan, M. Enos, E. Korkmazhan, S. Muennich, D.-H. Chen, M. V. Gammons, M. Vasishtha, M. Bienz, A. R. Dunn, G. Skiniotis, W. I. Weis

The paper shows that Dvl and Axin oligomerization dynamics regulate Wnt/β-catenin signaling efficiency by controlling β-catenin phosphorylation inhibition.

bioRxiv · Apr 1, 2020Biochemistry

eIF5B gates the transition from translation initiation to elongation

J. Wang, A. G. Johnson, C. P. Lapointe, J. Choi, A. Prabhakar, D.-H. Chen, A. N. Petrov, J. D. Puglisi

The paper investigates how eIF5B facilitates the transition from translation initiation to elongation in yeast using single-molecule fluorescence microscopy.

bioRxiv · Mar 23, 2019Biochemistry