TAK1 Regulates Endothelial Integrity Through Stabilization of Junctions via GSK3β and FoxO1
S. C. Regmi, D. Soni, D.-M. Wang, S. M. Vogel, A. B. Malik, C. Tiruppathi
This study identifies the TAK1-AKT-GSK3β-FoxO1 pathway as critical for maintaining endothelial barrier integrity and preventing vascular leak during sepsis.
bioRxiv · Sep 27, 2019 · PreprintCell Biology