Author

C. Tiruppathi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Malik· 3 shared P. T. Toth· 3 shared D.-M. Wang· 2 shared J. Rehman· 2 shared S. C. Regmi· 2 shared S. M. Vogel· 2 shared B. Joshi· 1 shared D. Mehta· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

A. B. Malik

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses

P. Gajwani, L. Wang, S. Srivastava, Z. Ye, Y.-M. Kim, S. Krantz, D. Wang, C. Tiruppathi, P. T. Toth, J. Rehman

This study identifies endothelial mitophagy as a source of mitochondrial formyl proteins that activate neutrophils and contribute to lung inflammation.

bioRxiv · Aug 7, 2022 · PreprintCell Biology

Computer-Vision Stabilized Intravital Imaging Reveals Lung Capillary Neutrophil Dynamics Crucial for Lung Host-Defense Function

Y. Tsukasaki, K. Bachmaier, J. C. Joshi, B. Joshi, P. T. Toth, Z. Hong, S. Nepal, M. Gunzer, J. Cho, D. Mehta, C. Tiruppathi, S. Pinho, J. Rehman, A. B. Malik

This study uses CASTii to analyze lung capillary neutrophil dynamics, revealing their role in host defense and response to infection.

bioRxiv · Apr 19, 2021 · PreprintMicrobiology

TAK1 Regulates Endothelial Integrity Through Stabilization of Junctions via GSK3β and FoxO1

S. C. Regmi, D. Soni, D.-M. Wang, S. M. Vogel, A. B. Malik, C. Tiruppathi

This study identifies the TAK1-AKT-GSK3β-FoxO1 pathway as critical for maintaining endothelial barrier integrity and preventing vascular leak during sepsis.

bioRxiv · Sep 27, 2019 · PreprintCell Biology

EphB1 in Endothelial Cells Regulates Caveolae Formation and Endocytosis

C. Tiruppathi, S. C. Regmi, D.-M. Wang, G. C. H. Mo, P. T. Toth, S. M. Vogel, R. V. Stan, M. Henkemeyer, R. D. Minshall, A. B. Malik

This study shows that EphB1 in endothelial cells regulates caveolae formation and endocytosis by interacting with caveolin-1 and modulating Src-dependent phosphorylation.

bioRxiv · Apr 26, 2019 · PreprintCell Biology