Author

D. Soni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. K. Mukherjee· 2 shared A. Sengupta· 2 shared A. Singh· 2 shared D. J. Dowling· 2 shared D. Khanna· 2 shared E. Nanishi· 2 shared M. De Leon· 2 shared O. Levy· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. K. Mukherjee

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Author profile →

5 papers

Recent·Most cited

Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2

A. Sengupta, S. Vinayagamurthy, D. Soni, R. Deb, A. K. Mukherjee, S. Dutta, J. Jaiswal, M. Yadav, S. Sharma, S. Bagri, S. S. Roy, P. Poonia, A. Singh, D. Khanna, A. K. Bhatt, , S. Chowdhury

This paper shows telomere length regulates hTERT expression by modulating TRF2 binding and PRC2-mediated repression, revealing a self-regulatory mechanism in cancer.

bioRxiv · Oct 9, 2023 · PreprintCancer Biology

Adjuvant Discovery via a High Throughput Screen using Human Primary Mononuclear Cells

K. Chew, B. Lee, S. Van Haren, E. Nanishi, T. R. O'Meara, J. B. Splaine, M. De Leon, D. Soni, H.-S. R. Seo, S. Dhe-Paganon, A. Ozonoff, J. A. Smith, O. Levy, D. J. Dowling

This paper describes a high-throughput screening method using human PBMCs to identify adjuvant candidates, resulting in a lead compound with in vivo adjuvanticity.

bioRxiv · Jun 17, 2022 · PreprintImmunology

Shaping neonatal immunization by tuning delivery of synergistic adjuvants via nanocarriers

S. Barman, F. Borriello, B. Brook, C. Pietrasanta, M. De Leon, C. Sweitzer, M. Menon, S. D. van Haren, D. Soni, Y. Saito, E. Nanishi, S. Yi, S. Bobbala, O. Levy, E. A. Scott, D. J. Dowling

This study identifies synergistic adjuvants for neonatal immunization using nanocarriers, showing enhanced Th1 bias and humoral responses in mice.

bioRxiv · Jun 3, 2022Immunology

Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

A. K. Mukherjee, S. Dutta, A. Singh, S. Sharma, S. S. Roy, A. Sengupta, M. Chatterjee, S. Vinayagamurthy, S. Bagri, D. Khanna, M. Verma, D. Soni, A. Budharaja, S. K. Bhisade, V. anand, , S. Chowdhury

The paper shows that telomere length modulates IL1R1 expression via TRF2 binding, affecting immune signaling and macrophage infiltration in TNBC.

bioRxiv · Dec 7, 2021 · PreprintCancer Biology

TAK1 Regulates Endothelial Integrity Through Stabilization of Junctions via GSK3β and FoxO1

S. C. Regmi, D. Soni, D.-M. Wang, S. M. Vogel, A. B. Malik, C. Tiruppathi

This study identifies the TAK1-AKT-GSK3β-FoxO1 pathway as critical for maintaining endothelial barrier integrity and preventing vascular leak during sepsis.

bioRxiv · Sep 27, 2019 · PreprintCell Biology