Author

Dan Takahashi

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Biology Disciplines

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Biochemistry· 1

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Basel MansouriD· 1 shared Binil Benny· 1 shared Shayoni Dutta· 1 shared Sifat Ahmed· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Basel MansourORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 8, 2026

From Predicted Ki to Surrogate IC50: Similarity-Guided Empirical Calibration of Drug Target Affinity Predictions

Basel Mansour, Shayoni Dutta, Binil Benny…·Dan Takahashi

The paper calibrates drug target affinity predictions to align with IC50 values using similarity-guided methods, reducing median fold error across kinase and non-kinase panels.

DOI 10.64898/2026.09.04.749433

proteomicsmetagenomics

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